华西医学

华西医学

鼻咽癌调强放射治疗对重要危及器官的放射性晚期毒性

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鼻咽癌好发于东南亚及我国南方地区,目前调强放射治疗(放疗)是鼻咽癌的标准治疗方式。自调强放疗开展以来,大量的鼻咽癌幸存者从中获益,但仍然有部分患者出现放射性晚期毒性反应,尤其是局部晚期患者,给患者的生活质量带来不良的影响。因此在控制肿瘤的前提下,如何更好地保护重要的危及器官是目前调强放疗的重点。该文就鼻咽癌调强放疗危及器官的放射性晚期毒性进行综述。

Nasopharyngeal carcinoma (NPC) is rather common in Southeast Asia and Southern China. The standard treatment for NPC is intensity-modulated radiotherapy (IMRT). A large number of the NPC survivors benefit from the IMRT, while some suffer from the late toxicities which can be life-threatening or significantly erode the patients’ quality of life and functional status, especially in the locally advanced NPC. Nowadays the late radiotherapy-related toxicities have been the most important concern for the radiotherapists and patients, who look forward to the better long-term tumor local control and overall survival. Therefore, we carried out a review about the late radiotherapy-related toxicities of the vital organs at risk after IMRT for NPC patients.

关键词: 鼻咽癌; 调强放射治疗; 危及器官; 放射性晚期毒性

Key words: Nasopharyngeal carcinoma; Intensity-modulated radiotherapy; Organ at risk; Late radiotherapy-related toxicity

引用本文: 覃蕾, 李燕, 陈念永. 鼻咽癌调强放射治疗对重要危及器官的放射性晚期毒性. 华西医学, 2018, 33(4): 449-453. doi: 10.7507/1002-0179.201706117 复制

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