华西医学

华西医学

中国急性肾损伤的防治策略

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急性肾损伤(acute kidney injury,AKI)作为复杂重症肾脏疾病一直是国际国内研究的焦点和热点。我国在 AKI 流行病学的研究领域已经取得长足进步,初步明确了我国 AKI 的发病率、地域分布特征及危险因素等,但进一步的 AKI 预防和治疗的问题随之而来。针对 AKI 疾病本身的高死亡率和高致残率的诊治,该文汇总并解析了我国 AKI 患者防治的两大难题:生物标志物早期预警和 AKI 治疗策略,并对目前的新观点和研究进展进行综述。目的是使中国肾脏病学者和专科医生明确 AKI 的防治重点,规范 AKI 的防治策略,提出我国 AKI 防治未来研究的方向,探寻适合我国 AKI 的诊断标准和诊疗规范。

Acute kidney injury (AKI), as a complex and severe kidney disease, has always been the hotspot of research. The epidemiological research of AKI in China has made significant progress, including initially reports on the domestic incidence of AKI, geographical distribution and risk factors; however, accompanying challenges like AKI prevention and treatment emerge. For improvement of the diagnosis and treatment of the AKI, this article summarizes and analyses the two challenges: early warning biomarkers and AKI treatment strategies, based on new ideas and research progress. The aim is to make Chinese nephrology scholars and specialists realize the focus of AKI prevention and protection of renal function, to standardize the treatment strategy of AKI, and to put forward the direction of future research.

关键词: 急性肾损伤; 生物标志物; 肾脏替代治疗; 治疗策略

Key words: Acute kidney injury; Biomarkers; Renal replacement therapy; Treatment strategies

引用本文: 冯哲, 陈香美. 中国急性肾损伤的防治策略. 华西医学, 2018, 33(7): 777-781. doi: 10.7507/1002-0179.201806095 复制

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