华西医学

华西医学

葡萄膜黑色素瘤诊疗进展

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葡萄膜黑色素瘤是成人最常见的眼内原发恶性肿瘤,虽然相对罕见,但极度恶性,且治疗效果不佳。尽管目前针对其原发病灶的治疗可以达理想的局部控制,但仍然有近一半的患者发生远处转移。此文结合当前诊疗技术的新进展,就葡萄膜黑色素瘤的流行病学、基因状态、诊断、原发疾病及转移病灶的治疗和预后作一综述。

Uveal melanoma is the most common primary intraocular malignancy in adults. Although it is relatively rare, it is extremely malignant, with poor treatment effect. The current treatment for primary lesions can achieve ideal local control, but there are still nearly half of the patients with distant metastasis. This article reviews the epidemiology, genetic status, diagnosis, treatment and prognosis of uveal melanoma in combination with recent advances in diagnostic and therapeutic techniques.

关键词: 葡萄膜黑色素瘤; 基因; 治疗; 预后

Key words: Uveal melanoma; Gene; Therapy; Prognosis

引用本文: 向中正, 刘磊. 葡萄膜黑色素瘤诊疗进展. 华西医学, 2018, 33(11): 1433-1440. doi: 10.7507/1002-0179.201810077 复制

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