华西医学

华西医学

外源性过敏性肺泡炎的临床治疗进展

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外源性过敏性肺泡炎是由于易感人群反复吸入各种具有抗原性的有机粉尘、低分子量化学物质等所引起的 Ⅲ 型或 Ⅳ 型变态反应性肺炎的总称,其病变累及肺泡、肺间质和气道,临床上以咳嗽、咳痰和呼吸困难等为主要临床表现。临床上将外源性过敏性肺泡炎分为急性型、亚急性型和慢性型。外源性过敏性肺泡炎会对患者的肺功能造成较大影响,因此早期及时的治疗可以改善患者的临床症状、抑制病情的发展,目前提出的治疗方案主要是避免接触抗原、糖皮质激素治疗、免疫抑制剂治疗、抗纤维化治疗以及肺移植。

Extrinsic allergic alveolitis is a general term for type Ⅲ or Ⅳ allergic pneumonia caused by repeated inhalation of various antigenic organic dusts and low molecular weight chemicals in susceptible people. The lesions involve alveolar, pulmonary interstitial, and airway. The main clinical manifestations are cough, expectoration, and dyspnea. Clinically, extrinsic allergic alveolitis is classified into acute, subacute, and chronic forms. Extrinsic allergic alveolitis has a great impact on the pulmonary function of patients. Timely treatment will improve clinical symptoms and inhibit the development of disease. The current treatment plan is mainly avoiding exposure to antigen, glucocorticoid therapy, immunosuppressive therapy, anti-fibrotic therapy, and lung transplantation.

关键词: 外源性过敏性肺泡炎; 临床治疗; 进展

Key words: Extrinsic allergic alveolitis; Clinical treatment; Progress

引用本文: 张维, 罗凤鸣. 外源性过敏性肺泡炎的临床治疗进展. 华西医学, 2019, 34(1): 82-85. doi: 10.7507/1002-0179.201812155 复制

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