华西医学

华西医学

2018 年 V3 版 NCCN 非小细胞肺癌指南更新要点解读

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该文对 2018.V3 版《NCCN 非小细胞肺癌诊治指南》进行解读。与 2017.V9 版《NCCN 非小细胞肺癌诊治指南》相比,新版指南基于最新的循证医学证据,以分子分型和靶向治疗进展为主,规范了病理评估原则、分子检测方法、靶向耐药后续治疗,以及驱动基因阳性患者的免疫治疗选择等,并更新了分期系统,有助于更高效、更精准地指导临床实践。

This article interprets the 2018.V3 version of NCCN guidelines for the diagnosis and treatment of non-small cell lung cancer. Compared with the 2017.V9 version of the guidelines, the new version has been updated based on the latest evidence-based evidence, laying the emphasis on genotyping and targeted therapy, and standardizes the principles of pathological evaluation and molecular detection, systematically recommends treatment after resistance to targeted therapy, and specifies the population with driver gene alterations for immunotherapy. All of which could guide clinical practice with higher efficacy more precisely.

关键词: 非小细胞肺癌; NCCN 指南; 2018.V3 更新

Key words: Non-small cell lung cancer; NCCN Guideline; 2018 V3 update

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